I am an Assistant Professor of Psychology at the Department of Psychology & Communication at the University of Idaho. My main areas of research are on using statistical modeling to better understand psychological disorders, especially on the predictive modeling of psychiatric treatment outcomes, aggregation of epidemiological and clinical trial data, and modeling the processes of change over the course of treatments for depression.
As of Fall 2025, I am currently recruiting a graduate student and a postdoctoral fellow for a Department of Defense funded research project on the statistical modeling of PTSD risk.
Colin Xu
Department of Psychology and Communication
875 Perimeter Drive, MS 3043
University of Idaho
Moscow, Idaho 83844
Email: colinxu@uidaho.edu
Kim, T., Xu, C., Amsterdam, J. (2025). Comparison of effectiveness and side effects of selegiline transdermal system versus oral monoamine oxidase inhibitors and tricyclic antidepressants for treatment-resistant depression. Journal of Affective Disorders, 376, 47-51 https://doi.org/10.1016/j.jad.2025.02.003 PDF
Kim, T. & Xu, C. (2024). Not all types of depressed patients who persist with their antidepressant treatment improve in side effect complaints: A comparison of treatment completers and dropouts in the STAR*D trial. Acta Psychiatrica Scandinavica, 151(2): 152-162. https://doi.org/10.1111/acps.13764 PDF
Amsterdam, J., & Xu, C. (2023). Multi-trial, aggregated, individual participant data mega-analysis of short-term antidepressant versus mood stabilizer monotherapy of bipolar type II major depressive episode. Bipolar Disorders., 26(3), 255-264. https://doi.org/10.1111/bdi.13378 PDF
Xu, C., Miao, L., Turner, D., & DeRubeis, R. (2023). Urbanicity and depression: A global meta-analysis. Journal of Affective Disorders, 340, 299-311. https://doi.org/10.1016/j.jad.2023.08.030 PDF
Pigott, H. E., Kim, T., Xu, C., Kirsch, I., & Amsterdam, J. (2023). What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR* D study's patient-level data with fidelity to the original research protocol. BMJ open, 13(7), e063095. http://doi.org/10.1136/bmjopen-2022-063095 PDF
Bredemeier, K., Larsen, S., Shivakumar, G., Grubbs, K., McLean, C., Tress, C., Rosenfield, D., DeRubeis, R., Xu, C., Foa, E., Morland, L., Pai, A., Tsao, C., Crawford, J., Weitz, E., Mayinja, L., Feler, B., Wachsman, T., Lupo, M., Hooper, V., … Thase, M. (2022). A comparison of prolonged exposure therapy, pharmacotherapy, and their combination for PTSD: What works best and for whom; study protocol for a randomized trial. Contemporary Clinical Trials, 119, 106850. https://doi.org/10.1016/j.cct.2022.106850 PDF
Kim, T. T., Xu, C., & DeRubeis, R. J. (2022). Mapping Female Patients’ Judgments of Satisfaction to Hypothetical Changes in Depression Symptom Severity. Behavior Therapy, 53(2), 392-399. https://doi.org/10.1016/j.beth.2021.10.003 PDF
Kim, T. T., Xu, C., & Derubeis, R. J. (2022). Patients’ judgments of the importance of treatment-induced reductions in symptoms of depression: The role of specific symptoms, magnitudes of change, and post-treatment levels. Psychotherapy Research, 32(3), 404-413. https://doi.org/10.1080/10503307.2021.1938731 PDF
Xu, C., Gelberg, H., & DeRubeis, R. J. (2021). Emotion regulation strategy correlates with discrete state emotion in major depression. Anxiety, Stress, & Coping, 1-12. https://doi.org/10.1080/10615806.2021.2015578 PDF
Khazanov, G. K., Xu, C., Hollon, S. D., DeRubeis, R. J., & Thase, M. E. (2021). Adding cognitive therapy to antidepressant medications decreases suicidal ideation. Journal of Affective Disorders, 281, 183-191. https://doi.org/10.1016/j.jad.2020.12.032 PDF
DeRubeis, R. J., Zajecka, J., Shelton, R. C., Amsterdam, J. D., Fawcett, J., Xu, C., ... & Hollon, S. D. (2020). Prevention of recurrence after recovery from a major depressive episode with antidepressant medication alone or in combination with cognitive behavioral therapy: a Phase 2 randomized clinical trial. JAMA Psychiatry, 77(3), 237-245. https://doi.org/10.1001/jamapsychiatry.2019.3900 PDF
Dunn, B. D., German, R. E., Khazanov, G., Xu, C., Hollon, S. D., & DeRubeis, R. J. (2020). Changes in positive and negative affect during pharmacological treatment and cognitive therapy for major depressive disorder: A secondary analysis of two randomized controlled trials. Clinical Psychological Science, 8(1), 36-51. https://doi.org/10.1177/2167702619863427 PDF
Khazanov, G. K., Xu, C., Dunn, B. D., Cohen, Z. D., DeRubeis, R. J., & Hollon, S. D. (2020). Distress and anhedonia as predictors of depression treatment outcome: a secondary analysis of a randomized clinical trial. Behaviour Research and Therapy, 125, 103507. https://doi.org/10.1016/j.brat.2019.103507 PDF
Kim, T., Xu, C., Amsterdam, J. D. (2019). Relative effectiveness of tricyclic antidepressant versus monoamine oxidase inhibitor monotherapy for treatment-resistant depression. Journal of Affective Disorders 250, 199-203. https://doi.org/10.1016/j.jad.2019.03.028 PDF
Fung, K., Xu, C., Glazier, B. L., Parsons, C. A., Alden, L. E. (2016). Research in Clinical Psychology: Social Exclusion in Clinical Samples. P. Riva & J. Eck (Eds.) Social Exclusion: Psychological Approaches to Understanding and Reducing Its Impact. Springer. https://doi.org/10.1007/978-3-319-33033-4_8 PDF
Xu, Colin & Kim, Thomas. No, Your Patients Are Not Wrong: Sometimes Antidepressant Side Effects Do Not Get Better. Cover article in Psychiatric Times, 42(4). April 2025. https://www.psychiatrictimes.com/view/no-your-patients-are-not-wrong-sometimes-antidepressant-side-effects-do-not-get-better
Dolan, Eric. Study challenges assumption of universal improvement in antidepressant side effects. Psypost. November 19, 2024. https://www.psypost.org/study-challenges-assumption-of-universal-improvement-in-antidepressant-side-effects/
Luten, Christine. U of I researcher challenges beliefs about antidepressant side effects. October 30, 2024. https://www.uidaho.edu/news/news-articles/news-releases/2024/103024-sideeffects
Pigott, E., Kim, T., Xu, C., Kirsch, I., Amsterdam, J. “STAR*D’s cumulative remission rate and why it still matters.” Cover article in Psychiatric Times, 41 (3). March 2024. https://www.psychiatrictimes.com/view/star-d-s-cumulative-remission-rate-and-why-it-still-matters
Miller, John J. “Exploring the STAR*D Controversy”. Cover article in Psychiatric Times, 41 (3). March 2024. https://www.psychiatrictimes.com/view/exploring-the-star-d-controversy
Miller, John J. “STAR*D Dethroned?”. Cover article in Psychiatric Times, 40 (12). December, 2023. https://www.psychiatrictimes.com/view/star-d-dethroned
Moser, Eric. “Five takeaways on urbanicity and depression research.” Penn Today. October 25th, 2023. https://penntoday.upenn.edu/news/psychology-five-takeaways-urbanicity-and-depression-research https://penntoday.upenn.edu/news/psychology-five-takeaways-urbanicity-and-depression-research
Podcast interview for Deutsche Welle, Science Unscripted. “Sadness and the city”. September 29, 2023. https://www.dw.com/en/mental-health-depression-30-more-likely-in-a-city/audio-66952505